Reproducible, scalable, and shareable analysis pipelines with bioinformatics workflow managers

L Wratten, A Wilm, J Göke - Nature methods, 2021 - nature.com
The rapid growth of high-throughput technologies has transformed biomedical research.
With the increasing amount and complexity of data, scalability and reproducibility have …

Plant genome sequences: past, present, future

PJ Kersey - Current opinion in plant biology, 2019 - Elsevier
Highlights•Almost 600 complete plant genome assemblies are now available in public
repositories.•New sequencing technologies are producing genome assemblies of …

The machine learning life cycle and the cloud: implications for drug discovery

O Spjuth, J Frid, A Hellander - Expert opinion on drug discovery, 2021 - Taylor & Francis
Introduction: Artificial intelligence (AI) and machine learning (ML) are increasingly used in
many aspects of drug discovery. Larger data sizes and methods such as Deep Neural …

DeepCell Kiosk: scaling deep learning–enabled cellular image analysis with Kubernetes

D Bannon, E Moen, M Schwartz, E Borba, T Kudo… - Nature …, 2021 - nature.com
Deep learning is transforming the analysis of biological images, but applying these models
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …

StreamFlow: cross-breeding cloud with HPC

I Colonnelli, B Cantalupo, I Merelli… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Workflows are among the most commonly used tools in a variety of execution environments.
Many of them target a specific environment; few of them make it possible to execute an …

PhenoMeNal: processing and analysis of metabolomics data in the cloud

K Peters, J Bradbury, S Bergmann, M Capuccini… - …, 2019 - academic.oup.com
Background Metabolomics is the comprehensive study of a multitude of small molecules to
gain insight into an organism's metabolism. The research field is dynamic and expanding …

[HTML][HTML] Cinco de Bio: A Low-Code Platform for Domain-Specific Workflows for Biomedical Imaging Research

C Brandon, S Boßelmann, A Singh, S Ryan… - …, 2024 - mdpi.com
Background: In biomedical imaging research, experimental biologists generate vast
amounts of data that require advanced computational analysis. Breakthroughs in …

KubeAdaptor: a docking framework for workflow containerization on Kubernetes

C Shan, Y Xia, Y Zhan, J Zhang - Future Generation Computer Systems, 2023 - Elsevier
As Kubernetes becomes the infrastructure of the cloud-native era, the integration of workflow
systems with Kubernetes is gaining more and more popularity. However, when migrating the …

[PDF][PDF] SciPipe: A workflow library for agile development of complex and dynamic bioinformatics pipelines

S Lampa, M Dahlö, J Alvarsson, O Spjuth - GigaScience, 2019 - academic.oup.com
Background The complex nature of biological data has driven the development of
specialized software tools. Scientific workflow management systems simplify the assembly of …

It's a Scheduling Affair: GROMACS in the Cloud with the KubeFlux Scheduler

C Misale, M Drocco, DJ Milroy… - … on Containers and …, 2021 - ieeexplore.ieee.org
In this work, we address the problem of running HPC workloads efficiently on Kubernetes
clusters. To do so, we compare the Kubernetes' default scheduler with KubeFlux, a …