Giardia lamblia, the cause of giardiasis, significantly impacts patients with metabolic
disorders related to insulin resistance (IR). Both giardiasis and metabolic disorders share …

Allergic diseases like asthma, allergic rhinitis and dermatitis pose a significant global health
burden, driving the search for novel therapies. The NLRP3 inflammasome, a key component …

Inflammatory diseases compromise a clinically common and diverse group of conditions,
causing detrimental effects on body functions. Gasdermins (GSDM) are pore-forming …

Atherosclerosis (AS) is the primary pathology behind various cardiovascular diseases and
the leading cause of death and disability globally. Recent evidence suggests that AS is a …

Inflammation plays a pivotal role in cancer development, with chronic inflammation
promoting tumor progression and treatment resistance, whereas acute inflammatory …

Hypoxic ischemic encephalopathy (HIE) is a primary cause of neonatal death and
disabilities. The pathogenetic process of HIE is closely associated with neuroinflammation …

This review elucidates the pivotal role of pyroptosis, triggered by gut microbiota, in the
development of multiple sclerosis (MS), emphasizing its significance within the gut-brain …

Acute pancreatitis (AP) remains a serious clinical condition, with current treatment options
being largely supportive. The discovery of inflammasomes, particularly the NOD-like …