Influences of polycyclic aromatic hydrocarbon on the epigenome toxicity and its applicability in human health risk assessment

DN Das, N Ravi - Environmental research, 2022 - Elsevier
The existence of polycyclic aromatic hydrocarbons (PAHs) in ambient air is an escalating
concern worldwide because of their ability to cause cancer and induce permanent changes …

[HTML][HTML] Air pollution-induced epigenetic changes: disease development and a possible link with hypersensitivity pneumonitis

S Mukherjee, S Dasgupta, PK Mishra… - … Science and Pollution …, 2021 - Springer
Air pollution is a serious threat to our health and has become one of the major causes of
many diseases including cardiovascular disease, respiratory disease, and cancer. The …

Empirical relationship between chromosomal damage and airborne particulate matter: A systematic review and meta-analysis of studies in exposed populations

FC da Silva Junior, LP de Araújo… - … Research/Reviews in …, 2023 - Elsevier
Ambient particulate matter (PM) has gained significant attention as an environmental risk
factor for human health. Although the association between ambient PM and micronucleus …

[HTML][HTML] Induction of innate immune memory by engineered nanoparticles in monocytes/macrophages: From hypothesis to reality

P Italiani, G Della Camera, D Boraschi - Frontiers in Immunology, 2020 - frontiersin.org
The capacity of engineered nanoparticles to activate cells of the innate immune system, in
particular monocytes and macrophages, is considered at the basis of their toxic/inflammatory …

[HTML][HTML] Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides

IC Dos Santos, JT da Silva, P Rohr… - … /Genetic Toxicology and …, 2022 - Elsevier
Brazil is one of the largest consumers of pesticides in the world. This high consumption has
resulted in higher potential health risk to agricultural farm workers due to occupational …

[HTML][HTML] World Trade Center exposure, DNA methylation changes, and cancer: a review of current evidence

S Tuminello, E Nguyen, N Durmus, R Alptekin… - Epigenomes, 2023 - mdpi.com
Introduction: Known carcinogens in the dust and fumes from the destruction of the World
Trade Center (WTC) towers on 9 November 2001 included metals, asbestos, and organic …

Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage

MD Arbo, SC Garcia, M Sarpa, FMRDS Junior… - … /Genetic Toxicology and …, 2022 - Elsevier
The evaluation of genotoxicity in workers exposed to different toxic agents is very important,
especially considering the association between these exposures in a chronic context and …

Induction of DNA damage as a consequence of occupational exposure to crystalline silica: A review and meta-analysis

G Wultsch, T Setayesh, M Kundi, M Kment… - … Research/Reviews in …, 2021 - Elsevier
About 40 million workers are occupationally exposed to crystalline silica (CS) which was
classified as a human carcinogen by the IARC. It is assumed that damage of the genetic …

Global and gene‐specific promoter methylation, and micronuclei induction in lead‐exposed workers: A cross‐sectional study

K Wang, Y Meng, T Wang, Y Tu, S Gong… - Environmental and …, 2021 - Wiley Online Library
Perturbation of epigenetic regulation is a well‐established mechanism for cancer but its role
for lead (Pb)‐associated toxicity has not been adequately investigated. We aimed to …

DNA methylation changes in promoter region of CDKN2A gene in workers exposed in construction environment

IR Silva, LFV Francisco, C Bernardo, MA Oliveira… - Biomarkers, 2020 - Taylor & Francis
Purpose Construction workers are exposed to a mixture of substances in the workplace
considered carcinogenic. This study aimed to characterise gene-specific changes in DNA …