According to the classical view of the nervous system, the numerically superior glial cells
have inferior roles in that they provide an ideal environment for neuronal-cell function …

The glutamate receptors mediate excitatory neurotransmission in the brain and are
important in memory acquisition, learning, and some neurodegenerative disorders. This …

Glutamate is the main excitatory neurotransmitter in the brain. For many years it has been
considered to act only on ligand-gated receptor channels—termed NMDA, AMPA and …

The mechanisms responsible for long-lasting, activitydependent decreases in synaptic
efficacy are not well understood. We haveexamined the initial steps required for the …

A readily releasable pool of quanta, tentatively identified with docked synaptic vesicles, has
been defined by analysis of the neurotransmitter release caused by application of hypertonic …

Glutamate receptors (GluRs) mediate most of the excitatory neurotransmission in the
mammalian central nervous system (CNS). In addition, they are involved in plastic changes …

The idea that astrocytes merely provide structural and trophic support for neurons has been
challenged by the demonstration that astrocytes can regulate neuronal calcium levels …

Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

Elevated levels of extracellular glutamate ([Glu] o) cause uncontrolled Ca2+ increases in
most neurons and are believed to mediate excitotoxic brain injury following stroke and other …

A cDNA clone for a new metabotropic glutamate receptor, termed mGluR6, was isolated
from a rat retinal cDNA library by cross-hybridization with the previously isolated cDNA clone …