BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Lipids and lipid derivatives for RNA delivery

Y Zhang, C Sun, C Wang, KE Jankovic… - Chemical reviews, 2021 - ACS Publications
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

PD-1/PD-L1 checkpoint inhibitors in tumor immunotherapy

J Liu, Z Chen, Y Li, W Zhao, JB Wu… - Frontiers in …, 2021 - frontiersin.org
Programmed death protein 1 (PD1) is a common immunosuppressive member on the
surface of T cells and plays an imperative part in downregulating the immune system and …

Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

[HTML][HTML] mRNA vaccines for COVID-19: what, why and how

JW Park, PNP Lagniton, Y Liu… - International journal of …, 2021 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease-19 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), has impacted human lives in the most …

Molecularly imprinted polymers: Antibody mimics for bioimaging and therapy

K Haupt, PX Medina Rangel, BTS Bui - Chemical reviews, 2020 - ACS Publications
Molecularly imprinted polymers (MIPs) are tailor-made chemical receptors that recognize
and bind target molecules with a high affinity and selectivity. MIPs came into the spotlight in …

Metal–organic framework nanocarriers for drug delivery in biomedical applications

Y Sun, L Zheng, Y Yang, X Qian, T Fu, X Li, Z Yang… - Nano-Micro Letters, 2020 - Springer
Investigation of metal–organic frameworks (MOFs) for biomedical applications has attracted
much attention in recent years. MOFs are regarded as a promising class of nanocarriers for …

Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

Click and bioorthogonal chemistry: the future of active targeting of nanoparticles for nanomedicines?

L Taiariol, C Chaix, C Farre, E Moreau - Chemical Reviews, 2021 - ACS Publications
Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …

Prospects and challenges of dynamic DNA nanostructures in biomedical applications

T Tian, Y Li, Y Lin - Bone Research, 2022 - nature.com
The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …