Objectives To explore the serotype distribution and drug resistance patterns of invasive
pneumococcal isolates from children under 5 years of age. Methods During a 32-month …

The purpose of this study was to develop a high-throughput method for the identification of
pneumococcal capsular types. Multiplex PCR combined with fragment analysis and …

Streptococcus pneumoniae is a potentially deadly human pathogen associated with high
morbidity, mortality and global economic burden. The universally used bacterial genotyping …

Background Asymptomatic nasopharyngeal carriage represents an important biological
marker for monitoring pneumococcal serotype distribution and evaluating vaccine effects …

We evaluated nasopharyngeal carriage of Streptococcus pneumoniae (pneumococci) in
nine Alaskan communities and used an algorithm combining microbiologic, serologic, and …

Background S. pneumoniae is the leading cause of community-acquired pneumonia in the
solid organ transplant recipient (SOTR); nevertheless, the prevalence of colonization and of …

Background The epidemiology of pneumococcal meningitis in the African 'meningitis belt'is
poorly studied. In order to ensure an effective vaccination strategy and post-vaccination …

We developed a new sequential multiplex-PCR-based typing scheme (MPBTS) for
pneumococcal capsular classification. The serogroup/type of 37 control isolates obtained by …

INTRODUCTION: Serotype surveillance of Streptococcus pneumoniae is indispensable for
evaluating the potential impact of pneumococcal conjugate vaccines. Serotyping by the …