The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …

Anticancer metallodrugs based on ruthenium and osmium are among the most investigated
and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …

Since our previous review, 1 there has been a tremendous development in the field of
carbazole alkaloids. New synthetic methodologies have been developed, existing …

A novel strategy in metallodrug discovery today is incorporating clinically approved drugs
into metal complexes as coordinating ligands. Using this strategy, various drugs have been …

Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

This review provides an introduction into the fascinating area of organometallic anticancer
compounds. Although the subject dates back many years, it has witnessed considerable …

Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …

The study of metal complexes for the treatment of cancer diseases has resulted in the
identification of some unique properties of ruthenium-based compounds. Among these …

Protein kinases have emerged as one of the most successful families of drug targets. To
date, most selective kinase inhibitors have been discovered serendipitously either through …