Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

The use of nanotechnology in medicine has the potential to have a major impact on human
health for the prevention, diagnosis, and treatment of diseases. One particular aspect of the …

The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

In spite of remarkable improvements in cancer treatments and survivorship, cancer still
remains as one of the major causes of death worldwide. Although current standards of care …

In recent years, gene therapy has made remarkable achievements in tumor treatment. In a
successfully cancer gene therapy, a smart gene delivery system is necessary for both …

Malignant tumor, the leading cause of death worldwide, poses a serious threat to human
health. For decades, natural product has been proven to be an essential source for novel …

Hepatocellular carcinoma (HCC) is a malignancy with a poor prognosis. Surgery combined
with chemotherapy has been recommended as a curative regimen for HCC. Nevertheless …

Hydrogels are soft materials consisting of a three-dimensional network of polymer chains.
Over the years, hydrogels with different compositions have been developed as drug carriers …

Glioblastoma multiforme is one of the most prevalent and malignant forms of central nervous
system tumors. The treatment of glioblastoma remains a great challenge due to its location …

Chemotherapeutics represent the standard treatment for a wide range of cancers. However,
these agents also affect healthy cells, thus leading to severe off-target effects. Given the non …