Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …

No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Clinical exome sequencing (CES) has become an increasingly popular diagnostic tool in
patients with heterogeneous genetic disorders, especially in those with neurocognitive …

In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical
regulator of cell function by virtue of specific physical, biochemical, and mechanical …

Extracellular matrix (ECM) remodeling occurs in response to various cardiac insults
including infarction, pressure overload and dilated myopathies. Each type of remodeling …

The developing heart is formed of two tissue layers separated by an extracellular matrix
(ECM) that provides chemical and physical signals to cardiac cells. While deposition of …

Background Neuregulin‐1β (NRG‐1β) is a growth factor critical for cardiac development and
repair with therapeutic potential for heart failure. We previously showed that the glial growth …

Aims Vertebrate heart development requires the complex morphogenesis of a linear tube to
form the mature organ, a process essential for correct cardiac form and function, requiring …

Integrins are a family of heterodimeric proteins expressed by cardiac fibroblasts and
cardiomyocytes that provide critical adhesive and signaling functions through their …