African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Entwined African and Asian genetic roots of medieval peoples of the Swahili coast

ES Brielle, J Fleisher, S Wynne-Jones, K Sirak… - Nature, 2023 - nature.com
The urban peoples of the Swahili coast traded across eastern Africa and the Indian Ocean
and were among the first practitioners of Islam among sub-Saharan people,. The extent to …

Genetic evidence and historical theories of the Asian and African origins of the present Malagasy population

M Heiske, O Alva, V Pereda-Loth… - Human molecular …, 2021 - academic.oup.com
The origin of the Malagasy population has been a subject of speculation since the 16th
century. Contributions of African, Asian, Indian, Melanesian, Arabic and Persian populations …

[HTML][HTML] Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim

F Menardo, LK Rutaihwa, M Zwyer, S Borrell… - …, 2021 - ncbi.nlm.nih.gov
Background: Lineage 1 (L1) and 3 (L3) are two lineages of the Mycobacterium tuberculosis
complex (MTBC) causing tuberculosis (TB) in humans. L1 and L3 are prevalent around the …

Genome-wide characterization of Arabian Peninsula populations: shedding light on the history of a fundamental bridge between continents

V Fernandes, N Brucato, JC Ferreira… - Molecular biology …, 2019 - academic.oup.com
Abstract The Arabian Peninsula (AP) was an important crossroad between Africa, Asia, and
Europe, being the cradle of the structure defining these main human population groups, and …

African mitochondrial haplogroup L7: a 100,000-year-old maternal human lineage discovered through reassessment and new sequencing

PA Maier, G Runfeldt, RJ Estes, MG Vilar - Scientific Reports, 2022 - nature.com
Archaeological and genomic evidence suggest that modern Homo sapiens have roamed the
planet for some 300–500 thousand years. In contrast, global human mitochondrial (mtDNA) …

Collagen fingerprinting traces the introduction of caprines to island Eastern Africa

C Culley, A Janzen, S Brown… - Royal Society …, 2021 - royalsocietypublishing.org
The human colonization of eastern Africa's near-and offshore islands was accompanied by
the translocation of several domestic, wild and commensal fauna, many of which had long …

[图书][B] African islands: A comparative archaeology

P Mitchell - 2022 - taylorfrancis.com
African Islands provides the first geographically and chronologically comprehensive
overview of the archaeology of African islands. This book draws archaeologically informed …

Tissue-and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo

M Derakhshan, NJ Kessler, M Ishida… - Nucleic acids …, 2022 - academic.oup.com
We analysed DNA methylation data from 30 datasets comprising 3474 individuals, 19
tissues and 8 ethnicities at CpGs covered by the Illumina450K array. We identified 4143 …

The loss of biodiversity in Madagascar is contemporaneous with major demographic events

O Alva, A Leroy, M Heiske, V Pereda-Loth, L Tisseyre… - Current Biology, 2022 - cell.com
Only 400 km off the coast of East Africa, the island of Madagascar is one of the last large
land masses to have been colonized by humans. While many questions surround the …