For successful colonization of the mammalian host, orally acquired bacteria must overcome
the extreme acidic stress (pH< 2.5) encountered during transit through the host stomach …

Computational protein design is advancing rapidly. Here we describe efficient routes starting
from validated parallel and antiparallel peptide assemblies to design two families of α …

Acid-adapted strains of Escherichia coli K-12 W3110 were obtained by serial culture in
medium buffered at pH 4.6 (MM Harden, A. He, K. Creamer, MW Clark, I. Hamdallah, KA …

Urinary tract infection (UTI) is a ubiquitous infectious condition, and uropathogenic
Escherichia coli (UPEC) is the predominant causative agent of UTI. Copper (Cu) is …

One of the first environmental cues sensed by a microbe as it enters a human host is an
upshift in temperature to 37° C. In this dynamic time point analysis, we demonstrate that this …

Enterobacteria are able to survive under stressful conditions within animals, such as acidic
conditions in the stomach, bile salts during transfer to the intestine and anaerobic conditions …

Abstract Enterohemorrhagic E. coli O157: H7 (EHEC) shorten the lifespan of Caenorhabditis
elegans compared to avirulent bacteria. Co-feeding EHEC with Enterococcus faecalis …

Food preservation by the use of essential oils (EOs) is being extensively studied because of
the antimicrobial properties of their individual constituents (ICs). Three resistant mutants …

Computational protein design is advancing rapidly. Here we describe efficient routes to two
families of α-helical-barrel proteins with central channels that bind small molecules. The …

Numerous commensal and pathogenic Gram‐negative and Gram‐positive bacteria are
referred to as neutralophiles because they grow best at pH levels close to neutrality. Thus …