The flavoenzyme nicotine oxidoreductase (NicA2) is a promising injectable treatment to aid
in the cessation of smoking, a behavior responsible for one in ten deaths worldwide. NicA2 …

Redox enzymes, mostly equipped with metal or organic cofactors, can vary their reactivity
with oxygen by orders of magnitude. Understanding how oxygen reactivity is controlled by …

Enzymatic therapy with nicotine-degrading enzyme is a new strategy in treating nicotine
addiction, which can reduce nicotine concentrations and weaken withdrawal in the rat …

The enzyme nicotine oxidoreductase (NicA2) is a member of the flavoprotein amine oxidase
family that uses a cytochrome c protein (CycN) as its oxidant instead of dioxygen, which is …

Nicotine oxidoreductase (NicA2) is a flavin-dependent enzyme that has the ability to
catalyze oxidation of nicotine to N-methylmyosmine. Though nicotine is a psychoactive …

hydroxy-(L)-nicotine oxidase, isolated from the organism Shinella sp. HZN7 (6HLNO-SE), is
an enzyme that during the catabolism of nicotine catalyzes the oxidation of (S)-6 …