A scoping review of biopsychosocial risk factors and co-morbidities for common spinal disorders

BN Green, CD Johnson, S Haldeman, E Griffith… - PLoS …, 2018 - journals.plos.org
Objective The purpose of this review was to identify risk factors, prognostic factors, and
comorbidities associated with common spinal disorders. Methods A scoping review of the …

Genetics and pathogenesis of idiopathic scoliosis

A Grauers, E Einarsdottir, P Gerdhem - Scoliosis and spinal disorders, 2016 - Springer
Idiopathic scoliosis (IS), the most common spinal deformity, affects otherwise healthy
children and adolescents during growth. The aetiology is still unknown, although genetic …

The role of endocrine hormones in the pathogenesis of adolescent idiopathic scoliosis

ZT Liang, CF Guo, J Li, HQ Zhang - The FASEB Journal, 2021 - Wiley Online Library
Adolescent idiopathic scoliosis (AIS) is a common spinal deformity characterized by
changes in the three‐dimensional structure of the spine. It usually initiates during puberty …

Association between genetic polymorphisms and risk of adolescent idiopathic scoliosis in case-control studies: a systematic review

E Terhune, P Heyn, C Piper, C Wethey… - Journal of Medical …, 2024 - jmg.bmj.com
Background Adolescent idiopathic scoliosis (AIS) is a structural lateral spinal curvature of≥
10° with rotation. Approximately 2%–3% of children across populations are affected with …

Methylation of estrogen receptor 2 (ESR2) in deep paravertebral muscles and its association with idiopathic scoliosis

M Chmielewska, P Janusz, M Andrusiewicz… - Scientific Reports, 2020 - nature.com
Idiopathic scoliosis (IS) is one of the most common spinal disorders in adolescents. Despite
many studies, the etiopathogenesis of IS is still poorly understood. In recent years, the role of …

Association between the estrogen receptor beta (ESR2) Rs1256120 single nucleotide polymorphism and adolescent idiopathic scoliosis: a systematic review and …

L Zhao, DM Roffey, S Chen - Spine, 2017 - journals.lww.com
Study Design. A systematic review and meta-analysis. Objective. The aim of this study was
to assess and synthesize the current evidence on the association between the rs1256120 …

ESR1 and PGR polymorphisms are associated with estrogen and progesterone receptor expression in breast tumors

DL Hertz, NL Henry, KM Kidwell… - Physiological …, 2016 - journals.physiology.org
Hormone receptor-positive (HR+) breast cancers express the estrogen (ERα) and/or
progesterone (PgR) receptors. Inherited single nucleotide polymorphisms (SNPs) in ESR1 …

Upregulated estrogen receptors impairs myogenesis and elevates adipogenesis related factor levels in the paravertebral muscles of patients with idiopathic scoliosis

Q Shu, G Yang, M Tang, C Guo, H Zhang, J Li - … and Biophysical Research …, 2023 - Elsevier
The prevalence of idiopathic scoliosis (IS) is 2–3% worldwide and is more common in girls.
Estrogen receptors (ERs) is supposed to be related to sex differences and development of …

内分泌激素在青少年特发性脊柱侧弯中的应用进展

王成龙, 武书丽 - 中国学校卫生, 2023 - cjsh.org.cn
青少年特发性脊柱侧弯(adolescent idiopathic scoliosis, AIS) 是最常见的脊柱畸形,
近几年发病率明显上升, 已成为威胁青少年健康的重要公共卫生问题. 青春期是人类生长发育 …

[HTML][HTML] Genetics and pathogenesis of scoliosis

E Petrosyan, J Fares, CS Ahuja, MS Lesniak… - North American Spine …, 2024 - Elsevier
Background Scoliosis is defined as a lateral spine curvature of at least 10° with vertebral
rotation, as seen on a posterior-anterior radiograph, often accompanied by reduced thoracic …