Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development
J Tschuck, V Padmanabhan Nair, A Galhoz… - Nature …, 2024 - nature.com
The development of functional neurons is a complex orchestration of multiple signaling
pathways controlling cell proliferation and differentiation. Because the balance of …
pathways controlling cell proliferation and differentiation. Because the balance of …
[HTML][HTML] Multitarget Effects of Nrf2 Signalling in the Brain: Common and Specific Functions in Different Cell Types
E Navarro, N Esteras - Antioxidants, 2024 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a crucial regulator of cellular defence
mechanisms, essential for maintaining the brain's health. Nrf2 supports mitochondrial …
mechanisms, essential for maintaining the brain's health. Nrf2 supports mitochondrial …
Age-dependent changes in Nrf2/Keap1 and target antioxidant protein expression correlate to lipoxidative adducts, and are modulated by dietary N-3 LCPUFA in the …
The brain has a high metabolism rate that may generate reactive oxygen and nitrogen
species. Consequently, nerve cells require highly efficient antioxidant defenses in order to …
species. Consequently, nerve cells require highly efficient antioxidant defenses in order to …
Piceatannol-3'-O-β-D-glucopyranoside inhibits neuroexcitotoxicity and ferroptosis through NMDAR/NRF2/BACH1/ACSL4 pathway in acute ischemic stroke
G Fan, J Liu, M Liu, Y Huang - Free Radical Biology and Medicine, 2024 - Elsevier
Background Neuronal protection is a well-established method of acute ischemic stroke (AIS)
treatment. The pharmacodynamic effect of Piceatannol-3'-O-β-D-glucopyranoside (Chinese …
treatment. The pharmacodynamic effect of Piceatannol-3'-O-β-D-glucopyranoside (Chinese …
Oxygen matters: Unraveling the role of oxygen in the neuronal response to cisplatin
J Crugeiras, A Calls, E Contreras… - Journal of the …, 2024 - Wiley Online Library
Abstract Background and Aims Cell culture is a fundamental experimental tool for
understanding cell physiology. However, translating these findings to in vivo settings has …
understanding cell physiology. However, translating these findings to in vivo settings has …
Dynamics in Redox-Active Molecules Following Ischemic Preconditioning in the Brain
T Lysikova, A Tomascova, M Kovalska, J Lehotsky… - Neurology …, 2024 - mdpi.com
It is well known that the brain is quite vulnerable to oxidative stress, initiating neuronal loss
after ischemia-reperfusion (IR) injury. A potent protective mechanism is ischemic …
after ischemia-reperfusion (IR) injury. A potent protective mechanism is ischemic …
The Redox Stress Test: A novel technique reveals oxidative stress in Parkinson's disease
AF Wright - Medical Research Archives, 2024 - esmed.org
Abstract A novel Redox Stress Test has been developed to identify symptoms of diseases
associated with oxidative stress by observing symptom changes induced by short-term …
associated with oxidative stress by observing symptom changes induced by short-term …