Viral replication is rapid and robust, but it is far from a chaotic process. Instead, successful
production of infectious progeny requires that events occur in the correct place and at the …

Of the 53 different human adenovirus (HAdV) serotypes belonging to species AG, a
significant number are associated with acute respiratory, gastrointestinal and ocular …

Non‐enveloped viruses of different types have evolved distinct mechanisms for penetrating
a cellular membrane during infection. Rotavirus penetration appears to occur by a process …

Reovirus, an oncolytic RNA virus exhibiting antiglioma activity, was shown in a previous
single institution phase 1 study found that the inoculation of the virus to be well tolerated in …

Viruses deliver their genome into host cells where they subsequently replicate and multiply.
A variety of relevant strategies have evolved by which viruses gain intracellular access and …

Hemolysis induced by antimicrobial polymers was examined to gain an understanding of the
mechanism of polymer toxicity to human cells. A series of cationic amphiphilic methacrylate …

Targeted delivery of nucleic acids into disease sites of human body has been attempted for
decades, but both viral and non-viral vectors are yet to meet our expectations. Safety …

Receptor‐mediated endocytosis is a major gate for pathogens into cells. In this study, we
analyzed the trafficking of human adenovirus type 2 and 5 (Ad2/5) and the escape‐defective …

Although the precise mechanism by which nonenveloped viruses penetrate biological
membranes is unclear, a more coherent understanding of this process is starting to emerge …

Cells are constantly challenged by pathogens (bacteria, virus, and fungi), and protein
aggregates or chemicals, which can provoke membrane damage at the plasma membrane …