Hot-spots of Mcl-1 protein: miniperspective

C Denis, J Sopková-de Oliveira Santos… - Journal of medicinal …, 2019 - ACS Publications
Protein–protein interactions (PPIs) control many important physiological processes within
human cells. Apoptosis or programmed cell death is closely regulated by pro-and …

[HTML][HTML] A proteome-scale map of the human interactome network

T Rolland, M Taşan, B Charloteaux, SJ Pevzner… - Cell, 2014 - cell.com
Just as reference genome sequences revolutionized human genetics, reference maps of
interactome networks will be critical to fully understand genotype-phenotype relationships …

Investigations of enzyme-catalysed reactions with combined quantum mechanics/molecular mechanics (QM/MM) methods

KE Ranaghan, AJ Mulholland - International Reviews in Physical …, 2010 - Taylor & Francis
Combined quantum mechanics/molecular mechanics (QM/MM or QM-MM) methods are an
excellent approach for modelling the mechanisms of enzyme-catalysed reactions. QM/MM …

ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins

E De Castro, CJA Sigrist, A Gattiker… - Nucleic acids …, 2006 - academic.oup.com
Abstract ScanProsite—http://www. expasy. org/tools/scanprosite/—is a new and improved
version of the web-based tool for detecting PROSITE signature matches in protein …

[图书][B] Enzymes in industry: production and applications

W Aehle - 2007 - books.google.com
Leading experts from all over the world present an overview of the use of enzymes in
industry for:-the production of bulk products, such as glucose, or fructose-food processing …

Nicotinic cholinergic system and COVID-19: in silico identification of an interaction between SARS-CoV-2 and nicotinic receptors with potential therapeutic targeting …

K Farsalinos, E Eliopoulos, DD Leonidas… - International journal of …, 2020 - mdpi.com
While SARS-CoV-2 uses angiotensin converting enzyme 2 (ACE2) as the receptor for cell
entry, it is important to examine other potential interactions between the virus and other cell …

Synthesis of novel 2-mercapto benzothiazole and 1, 2, 3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities

S Shafi, MM Alam, N Mulakayala, C Mulakayala… - European journal of …, 2012 - Elsevier
A focused library of novel bis-heterocycles encompassing 2-mercapto benzothiazole and 1,
2, 3-triazoles were synthesized using click chemistry approach. The synthesized compounds …

The RCSB PDB information portal for structural genomics

A Kouranov, L Xie, J de la Cruz, L Chen… - Nucleic acids …, 2006 - academic.oup.com
Abstract The RCSB Protein Data Bank (PDB) offers online tools, summary reports and target
information related to the worldwide structural genomics initiatives from its portal at http://sg …

ProTherm and ProNIT: thermodynamic databases for proteins and protein–nucleic acid interactions

MDS Kumar, KA Bava, MM Gromiha… - Nucleic acids …, 2006 - academic.oup.com
ProTherm and ProNIT are two thermodynamic databases that contain experimentally
determined thermodynamic parameters of protein stability and protein–nucleic acid …

PISCES: recent improvements to a PDB sequence culling server

G Wang, RL Dunbrack - Nucleic acids research, 2005 - academic.oup.com
PISCES is a database server for producing lists of sequences from the Protein Data Bank
(PDB) using a number of entry-and chain-specific criteria and mutual sequence identity. Our …