Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Lactobacillus iners: friend or foe?

MI Petrova, G Reid, M Vaneechoutte, S Lebeer - Trends in microbiology, 2017 - cell.com
The vaginal microbial community is typically characterized by abundant lactobacilli.
Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal …

Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health

MI Petrova, E Lievens, S Malik, N Imholz… - Frontiers in …, 2015 - frontiersin.org
The human body is colonized by a vast number of microorganisms collectively referred to as
the human microbiota. One of the main microbiota body sites is the female genital tract …

From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

D Lebeaux, A Chauhan, O Rendueles, C Beloin - Pathogens, 2013 - mdpi.com
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Does the vaginal microbiota play a role in the development of cervical cancer?

M Kyrgiou, A Mitra, AB Moscicki - Translational Research, 2017 - Elsevier
Persistent infection with oncogenic human papillomavirus (HPV) is necessary but not
sufficient for the development of cervical cancer. The factors promoting persistence as well …

Bacterial vaginosis: current diagnostic avenues and future opportunities

MJ Redelinghuys, J Geldenhuys, H Jung… - Frontiers in cellular and …, 2020 - frontiersin.org
A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen
peroxide producing bacteria, which provide protection against infections by maintaining a …

Characterisation of the human uterine microbiome in non-pregnant women through deep sequencing of the V1-2 region of the 16S rRNA gene

H Verstraelen, R Vilchez-Vargas, F Desimpel… - PeerJ, 2016 - peerj.com
Background. It is widely assumed that the uterine cavity in non-pregnant women is
physiologically sterile, also as a premise to the long-held view that human infants develop in …

The vaginal microbiota: what have we learned after a decade of molecular characterization?

JHHM Van De Wijgert, H Borgdorff, R Verhelst… - PloS one, 2014 - journals.plos.org
We conducted a systematic review of the Medline database (US National Library of
Medicine, National Institutes of Health, Bethesda, MD, USA) to determine if consistent …

Vaginal microbiota

W Mendling - Microbiota of the human body: Implications in health …, 2016 - Springer
The knowledge about the normal and abnormal vaginal microbiome has changed over the
last years. Culturing techniques are not suitable any more for determination of a normal or …

Unveiling the role of Gardnerella vaginalis in polymicrobial Bacterial Vaginosis biofilms: the impact of other vaginal pathogens living as neighbors

J Castro, D Machado, N Cerca - The ISME journal, 2019 - academic.oup.com
Bacterial vaginosis (BV) is characterized by a highly structured polymicrobial biofilm, which
is strongly adhered to the vaginal epithelium and primarily consists of the bacterium …