The artificial pancreas (AP), known as closed-loop control of blood glucose in diabetes, is a
system combining a glucose sensor, a control algorithm, and an insulin infusion device. AP …

The control of diabetes is an interdisciplinary endeavor, which includes a significant
biomedical engineering component, with traditions of success beginning in the early 1960s …

A simulation model of the glucose-insulin system in the postprandial state can be useful in
several circumstances, including testing of glucose sensors, insulin infusion algorithms and …

Arguably, a minimally invasive system using subcutaneous (sc) continuous glucose
monitoring (CGM) and sc insulin delivery via insulin pump would be a most feasible step to …

A clinical model of glucose-insulin interaction in insulin-dependent diabetes mellitus has
been developed for patient and medical staff education. The model attempts to reflect the …

Background: A simulation model of the glucose—insulin system in normal life conditions can
be very useful in diabetes research, eg, testing insulin infusion algorithms and decision …

This article discusses closed-loop blood glucose regulation algorithms that use the
intravenous route for insulin delivery to insulin-dependent diabetic patients. Classical control …

Abstract The incidence of Diabetes Mellitus is on the rise worldwide, which exerts enormous
health toll on the population and enormous pressure on the healthcare systems. Now …

The validation process is an essential component of the modelling of in vivo endocrine and
metabolic systems. In the paper a validation study of a comprehensive model of the glucose …

The development of control-relevant models for a variety of biomedical engineering drug
delivery problems is reviewed in this paper. A summary of each control problem is followed …