The endoplasmic reticulum (ER) is a large, dynamic structure that serves many roles in the
cell including calcium storage, protein synthesis and lipid metabolism. The diverse functions …

Selective autophagy represents the major quality control mechanism that ensures proper
turnover of exhausted or harmful organelles, among them the endoplasmic reticulum (ER) …

Close appositions between the membrane of the endoplasmic reticulum (ER) and other
intracellular membranes have important functions in cell physiology. These include lipid …

In higher eukaryotes, the endoplasmic reticulum (ER) contains a network of membrane
tubules, which transitions into sheets during mitosis. Network formation involves curvature …

The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature
in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of …

The endoplasmic reticulum (ER) is an organelle that is responsible for many essential
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …

Eukaryotes characteristically organize their genome in a separate compartment, the
nucleus, which is surrounded by the nuclear envelope as a barrier. Ruptures of the nuclear …

A tendency in cell biology is to divide and conquer. For example, decades of painstaking
work have led to an understanding of endoplasmic reticulum (ER) and Golgi structure …

The nuclear pore complex (NPC) mediates all macromolecular transport across the nuclear
envelope. In higher eukaryotes that have an open mitosis, NPC s assemble at two points in …

The dynamic distribution of the microtubule (MT) cytoskeleton is crucial for the shape,
motility, and internal organization of eukaryotic cells. However, the basic principles that …