Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

A tutorial review: Metabolomics and partial least squares-discriminant analysis–a marriage of convenience or a shotgun wedding

PS Gromski, H Muhamadali, DI Ellis, Y Xu, E Correa… - Analytica chimica …, 2015 - Elsevier
The predominance of partial least squares-discriminant analysis (PLS-DA) used to analyze
metabolomics datasets (indeed, it is the most well-known tool to perform classification and …

Metabolomics for laboratory diagnostics

R Bujak, W Struck-Lewicka, MJ Markuszewski… - … of pharmaceutical and …, 2015 - Elsevier
Metabolomics is an emerging approach in a systems biology field. Due to continuous
development in advanced analytical techniques and in bioinformatics, metabolomics has …

Metabolomics: small molecules that matter more

BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …

Fingerprinting food: current technologies for the detection of food adulteration and contamination

DI Ellis, VL Brewster, WB Dunn, JW Allwood… - Chemical Society …, 2012 - pubs.rsc.org
Major food adulteration and contamination events seem to occur with some regularity, such
as the widely publicised adulteration of milk products with melamine and the recent …

NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review

A Smolinska, L Blanchet, LMC Buydens… - Analytica chimica …, 2012 - Elsevier
Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

Metabolomics in exercise and sports: A systematic review

K Khoramipour, Ø Sandbakk, AH Keshteli, AA Gaeini… - Sports Medicine, 2022 - Springer
Background Metabolomics is a field of omics science that involves the comprehensive
measurement of small metabolites in biological samples. It is increasingly being used to …

[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world

DK Trivedi, KA Hollywood, R Goodacre - New horizons in translational …, 2017 - Elsevier
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …

The continuing value of twin studies in the omics era

J Van Dongen, PE Slagboom, HHM Draisma… - Nature Reviews …, 2012 - nature.com
The classical twin study has been a powerful heuristic in biomedical, psychiatric and
behavioural research for decades. Twin registries worldwide have collected biological …

NMR-based plant metabolomics: where do we stand, where do we go?

HK Kim, YH Choi, R Verpoorte - Trends in biotechnology, 2011 - cell.com
NMR-based metabolomics is an important tool for studying biological systems and has been
applied in various organisms, including animals, plants and microbes. NMR is able to …