[HTML][HTML] Small extracellular vesicles in cancer
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
Epigenetic and “redoxogenetic” adaptation to physical exercise
Exercise-induced adaptation is achieved by altering the epigenetic landscape of the entire
genome leading to the expression of genes involved in various processes including …
genome leading to the expression of genes involved in various processes including …
Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker
Epigenetic reprogramming in cancer genomes creates a distinct methylation landscape
encompassing clustered methylation at regulatory regions separated by large intergenic …
encompassing clustered methylation at regulatory regions separated by large intergenic …
The physics of epigenetics
In higher organisms, all cells share the same genome, but every cell expresses only a
limited and specific set of genes that defines the cell type. During cell division, not only the …
limited and specific set of genes that defines the cell type. During cell division, not only the …
Links between DNA methylation and nucleosome occupancy in the human genome
CK Collings, JN Anderson - Epigenetics & chromatin, 2017 - Springer
Background DNA methylation is an epigenetic modification that is enriched in
heterochromatin but depleted at active promoters and enhancers. However, the debate on …
heterochromatin but depleted at active promoters and enhancers. However, the debate on …
DNA methylation regulated nucleosome dynamics
A strong correlation between nucleosome positioning and DNA methylation patterns has
been reported in literature. However, the mechanistic model accounting for the correlation …
been reported in literature. However, the mechanistic model accounting for the correlation …
Direct DNA methylation profiling with an electric biosensor
DNA methylation is one of the principal epigenetic mechanisms that control gene expression
in humans, and its profiling provides critical information about health and disease. Current …
in humans, and its profiling provides critical information about health and disease. Current …
Simulation studies on signature interactions between cancer DNA and cysteamine-decorated AuNPs for universal cancer screening
W Phanchai, U Srikulwong, A Chuaephon… - ACS Applied Nano …, 2022 - ACS Publications
In cancer genomes, DNA methylation results in the formation of a distinct methylation
landscape (methylscape) characterized by clustered methylation at regulatory regions …
landscape (methylscape) characterized by clustered methylation at regulatory regions …
Hydroxymethylation of DNA influences nucleosomal conformation and stability in vitro
Background Hydroxymethylation of DNA at the C5 position of cytosine (5hmC) is recognized
as an important epigenetic mark. The molecular role of 5hmC in gene regulation, however …
as an important epigenetic mark. The molecular role of 5hmC in gene regulation, however …
CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level
The methylcytosine-binding domain 2 (MBD2) protein recruits the nucleosome remodeling
and deacetylase complex (NuRD) to methylated DNA to modify chromatin and regulate …
and deacetylase complex (NuRD) to methylated DNA to modify chromatin and regulate …