With the advent of mechanobiology, cell shape and forces have emerged as essential
elements of cell behavior and fate, in addition to biochemical factors such as growth factors …

Cell traction force plays a critical role in directing cellular functions, such as proliferation,
migration, and differentiation. Current understanding of cell traction force is largely derived …

Cell collectives must dynamically adapt to different biological contexts. For instance, in
homeostatic conditions, epithelia must establish a barrier between body compartments and …

Cellular rearrangements, as primary sources of tissue fluidization, facilitate topological
transitions during tissue morphogenesis. We study the role of intrinsic cell properties such as …

The ability of epithelial monolayers to self-organize into a dynamic polarized state, where
cells migrate in a uniform direction, is essential for tissue regeneration, development, and …

Epithelia consist of proliferating and differentiating cells that often display patterned
arrangements. However, the mechanism regulating these spatial arrangements remains …

Tissue spheroids are self-organised 3D cellular aggregates that serve as a versatile platform
in tissue engineering. While numerous high-throughput methods exist to characterise the …

Changes in cell fluidity have been observed in various cellular tissues and are strongly
linked to biological phenomena such as self-organization. Recent studies suggested variety …

Constraining collective cell migration in vitro using different types of engineered substrates
such as microstructured surfaces or adhesive patterns of different shapes and sizes often …

Background: E-cadherin is an important adhesion protein that plays a significant role in cell-
cell adhesion and tissue integrity in epithelial tissues. It regulates migration and signaling …