Type 2 diabetes and its impact on the immune system

A Berbudi, N Rahmadika, AI Tjahjadi… - Current diabetes …, 2020 - ingentaconnect.com
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic
disease is indicated by high blood glucose levels due to insufficient insulin production by the …

The effects of type 2 diabetes mellitus on organ metabolism and the immune system

G Daryabor, MR Atashzar, D Kabelitz, S Meri… - Frontiers in …, 2020 - frontiersin.org
Metabolic abnormalities such as dyslipidemia, hyperinsulinemia, or insulin resistance and
obesity play key roles in the induction and progression of type 2 diabetes mellitus (T2DM) …

Markers of oxidative stress during diabetes mellitus

BK Tiwari, KB Pandey, AB Abidi… - Journal of biomarkers, 2013 - Wiley Online Library
The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of
hyperglycemia due to defects in insulin secretion/action leads to a variety of complications …

Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16 Monocytes From COVID-19 Patients

SL Lage, EP Amaral, KL Hilligan, E Laidlaw… - Frontiers in …, 2022 - frontiersin.org
The poor outcome of the coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is
associated with systemic hyperinflammatory response and immunopathology. Although …

Type 2 Diabetes Mellitus and Altered Immune System Leading to Susceptibility to Pathogens, Especially Mycobacterium tuberculosis

S Ferlita, A Yegiazaryan, N Noori, G Lal… - Journal of clinical …, 2019 - mdpi.com
There has been an alarming increase in the incidence of Type 2 Diabetes Mellitus (T2DM)
worldwide. Uncontrolled T2DM can lead to alterations in the immune system, increasing the …

The diabetes pandemic and associated infections: suggestions for clinical microbiology

A Toniolo, G Cassani, A Puggioni, A Rossi… - … and Research in …, 2019 - journals.lww.com
There are 425 million people with diabetes mellitus in the world. By 2045, this figure will
grow to over 600 million. Diabetes mellitus is classified among noncommunicable diseases …

Diabetes and tuberculosis

BI Restrepo - Understanding the host immune response against …, 2018 - Springer
The worldwide increase in the prevalence of diabetes has been most notable in TB-endemic
countries and has led to the re-emerging importance of the association between these two …

Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections

K Hodgson, J Morris, T Bridson, B Govan, C Rush… - …, 2015 - Wiley Online Library
Diabetes has been recognized as an important risk factor for a variety of intracellular
bacterial infections, but research into the dysregulated immune mechanisms contributing to …

The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-19

SK Jain, R Parsanathan, SN Levine, JA Bocchini… - Free Radical Biology …, 2020 - Elsevier
There is a marked variation in mortality risk associated with COVID-19 infection in the
general population. Low socioeconomic status and other social determinants have been …

The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?

R Van Crevel, S Van De Vijver… - The lancet Diabetes & …, 2017 - thelancet.com
Tropical countries are experiencing a substantial rise in type 2 diabetes, which is often
undiagnosed or poorly controlled. Since diabetes is a risk factor for many infectious …