The control of mRNA stability is an important process that allows cells to not only limit, but
also rapidly adjust, the expression of regulatory factors whose over expression may be …

Anti-apoptotic B cell lymphoma 2 (BCL2) family members (BCL2, MCL1, BCLxL, BCLW, and
BFL1) are key players in the regulation of intrinsic apoptosis. Dysregulation of these proteins …

The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

Recent evidence suggests that gene expression may be regulated, at least in part, at post‐
transcriptional level by factors inducing the extremely rapid degradation of messenger …

Messenger ribonucleic acid (mRNA) turnover is a major control point in gene expression. In
mammals, many mRNAs encoding inflammatory cytokines, oncoproteins, and G‐protein …

Adenylate/uridylate-rich element (ARE)-mediated mRNA turnover is an important regulatory
component of gene expression for innate and specific immunity, in the hematopoietic …

A growing body of work demonstrates the importance of post-transcriptional control, in
particular translation initiation, in the overall regulation of gene expression. Here we focus …

Gene expression patterns in cancer cells are strongly influenced by posttranscriptional
mechanisms. RNA‐binding proteins (RBPs) play key roles in posttranscriptional gene …

AUF1 is a family of four proteins generated by alternative pre-mRNA splicing that form high
affinity complexes with AU-rich, mRNA-destabilizing sequences located within the 3 …

HT1080 cells stably expressing green fluorescent protein (GFP) linked to a 3′ terminal AU‐
rich element (ARE) proved to be a convenient system to study the dynamics of mRNA …