The vacuolar (H+)-ATPases (V-ATPases) are ATP-dependent proton pumps that acidify
intracellular compartments and are also present at the plasma membrane. They function in …

Transmembrane ATPases are membrane-bound enzyme complexes and ion transporters
that can be divided into F-, V-, and A-ATPases according to their structure. The V-ATPases …

The vacuolar ATPases (V-ATPases) are a family of proton pumps that couple ATP hydrolysis
to proton transport into intracellular compartments and across the plasma membrane. They …

V-ATPases are membrane-embedded protein complexes that function as ATP hydrolysis-
driven proton pumps. V-ATPases are the primary source of organellar acidification in all …

Epidemiological data indicate a constant worldwide increase in cancer mortality, although
the age of onset is increasing. Recent accumulation of genomic data on human cancer via …

Alterations in tumour metabolism and acid/base regulation result in the formation of a hostile
environment, which fosters tumour growth and metastasis. Acid/base homoeostasis in …

Abstract The Vacuolar ATPase (V-ATPase) is a proton pump responsible for controlling the
intracellular and extracellular pH of cells. The structure of V-ATPase has been highly …

Abstract The vacuolar H+-ATPases (V-ATPases) are essential, ATP-dependent proton
pumps present in a variety of eukaryotic cellular membranes. Intracellularly, V-ATPase …

Impairments in neural lysosomal-and autophagic-mediated degradation of cellular debris
contribute to neuritic dystrophy and synaptic loss. While these are well-characterized …

Abstract Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H+‐transporter that pumps
protons across intracellular and plasma membranes. It consists of a large multi‐subunit …