Yeast as carrier for drug delivery and vaccine construction

Y Tan, L Chen, K Li, B Lou, Y Liu, Z Liu - Journal of Controlled Release, 2022 - Elsevier
Yeast has been employed as an effective derived drug carrier as a unicellular
microorganism. Many research works have been devoted to the encapsulation of nucleic …

Yeast oral vaccines against infectious diseases

N Austriaco - Frontiers in Microbiology, 2023 - frontiersin.org
Vaccines that are delivered orally have several advantages over their counterparts that are
administered via injection. Despite the advantages of oral delivery, however, approved oral …

Expanding opportunities to engineer mucosal vaccination with biomaterials

HF Haddad, EF Roe, JH Collier - Biomaterials Science, 2023 - pubs.rsc.org
Mucosal vaccines are receiving increasing interest both for protecting against infectious
diseases and for inducing therapeutic immune responses to treat non-infectious diseases …

Improving expression and assembly of difficult-to-express heterologous proteins in Saccharomyces cerevisiae by culturing at a sub-physiological temperature

KK So, NMT Le, NL Nguyen, DH Kim - Microbial cell factories, 2023 - Springer
Background Escherichia coli heat labile toxin B subunit (LTB) is one of the most popular oral
vaccine adjuvants and intestine adsorption enhancers. It is often expressed as a fusion …

[HTML][HTML] A multiple-target mRNA-LNP vaccine induces protective immunity against experimental multi-serotype DENV in mice

L He, W Sun, L Yang, W Liu, J Li - Virologica Sinica, 2022 - Elsevier
Dengue virus (DENV) is a mosquito-borne virus with a rapid spread to humans, causing mild
to potentially fatal illness in hundreds of millions of people each year. Due to the large …

Novel and efficient yeast-based strategies for subunit vaccine delivery against COVID-19

Q Lang, N Huang, L Li, K Liu, H Chen, X Liu… - International Journal of …, 2025 - Elsevier
Yeast shows promise as a delivery system for drugs and vaccines due to its specific
targeting and immunogenic properties. The objective of this research is to create novel and …

Metabolic engineering of Saccharomyces cerevisiae for the biosynthesis of a fungal pigment from the phytopathogenic fungus Cladosporium phlei

Y Gwon, KK So, J Chun, DH Kim - Journal of Biological Engineering, 2024 - Springer
Background Cladosporium phlei is a phytopathogenic fungus that produces a pigment
called phleichrome. This fungal perylenequinone plays an important role in the production of …

Advantages of yeast-based recombinant protein technology as vaccine products against infectious diseases

CSW Lestari, G Novientri - IOP Conference Series: Earth and …, 2021 - iopscience.iop.org
The yeast expression system is widely used to produce functional recombinant proteins in
the biopharmaceutical industry, such as vaccine products. The expression system choices …

Expression of virus-like particles (VLPs) of foot-and-mouth disease virus (FMDV) using Saccharomyces cerevisiae

NMT Le, KK So, J Chun, DH Kim - Applied Microbiology and Biotechnology, 2024 - Springer
We engineered Saccharomyces cerevisiae to express structural proteins of foot-and-mouth
disease virus (FMDV) and produce virus-like particles (VLPs). The gene, which encodes four …

Mucosal vaccination: A promising alternative against flaviviruses

R Luria-Pérez, LA Sánchez-Vargas… - Frontiers in Cellular …, 2022 - frontiersin.org
The Flaviviridae are a family of positive-sense, single-stranded RNA enveloped viruses, and
their members belong to a single genus, Flavivirus. Flaviviruses are found in mosquitoes …