Thyroid hormones (THs) play an obligatory role in many fundamental processes underlying
brain development and maturation. The developing embryo/fetus is dependent on maternal …

Thyroid hormones are important during development of the mammalian brain, acting on
migration and differentiation of neural cells, synaptogenesis, and myelination. The actions of …

Objective To examine the relationship between specific thyroid abnormalities (subclinical
hypothyroidism, hypothyroxinaemia or elevated thyroid peroxidase antibody titres) in women …

Allan-Herndon-Dudley syndrome (AHDS), a severe form of psychomotor retardation with
abnormal thyroid hormone (TH) parameters, is linked to mutations in the TH-specific …

Through its actions on regulatory genes that form, grow and sculpt the brain, thyroid
hormone (TH) is essential for human brain development. Although much of what we know …

Background: An in-depth understanding of the fundamental principles that regulate thyroid
hormone homeostasis is critical for the development of new diagnostic and treatment …

The normal function of the nervous system is conditioned by the undisturbed function of the
thyroid gland and its hormones. Comprehensive clinical manifestations, including …

Cerebral selenium (Se) deficiency is associated with neurological phenotypes including
seizures and ataxia. We wanted to define whether neurons require selenoprotein …

Endothelial dysfunction is an important risk factor for cardiovascular disease, and it
represents the initial step in the pathogenesis of atherosclerosis. Failure to protect against …

Expression of selenoproteins is widespread in neurons of the central nervous system. There
is continuous evidence presented over decades that low levels of selenium or …