Spectral photon-counting computed tomography: a review on technical principles and clinical applications

M Tortora, L Gemini, I D'Iglio, L Ugga, G Spadarella… - Journal of …, 2022 - mdpi.com
Photon-counting computed tomography (CT) is a technology that has attracted increasing
interest in recent years since, thanks to new-generation detectors, it holds the promise to …

The role of imaging in osteoarthritis

EH Park, J Fritz - Best Practice & Research Clinical Rheumatology, 2023 - Elsevier
Osteoarthritis is a complex whole-organ disorder that involves molecular, anatomic, and
physiologic derangement. Advances in imaging techniques have expanded the role of …

Latest advancements in imaging techniques in OA

D Hayashi, FW Roemer, T Link, X Li… - Therapeutic …, 2022 - journals.sagepub.com
The osteoarthritis (OA) research community has been advocating a shift from radiography-
based screening criteria and outcome measures in OA clinical trials to a magnetic …

Quantification of cartilage and subchondral bone cysts on knee specimens based on a spectral photon-counting computed tomography

C Garcelon, J Abascal, C Olivier, S Uk… - Scientific Reports, 2023 - nature.com
Spectral photon-counting computed tomography (SPCCT) is a new technique with the
capability to provide mono-energetic (monoE) images with high signal to noise ratio. We …

[HTML][HTML] Osteoarthritis year in review 2022: imaging

S Demehri, A Kasaeian, FW Roemer… - Osteoarthritis and …, 2023 - Elsevier
Purpose This narrative review summarizes original research focusing on imaging in
osteoarthritis (OA) published between April 1st 2021 and March 31st 2022. We only …

Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—a proof of concept study

H Orava, P Paakkari, J Jäntti… - Journal of …, 2024 - Wiley Online Library
Cartilage and synovial fluid are challenging to observe separately in native computed
tomography (CT). We report the use of triple contrast agent (bismuth nanoparticles [BiNPs] …

Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

P Paakkari, SI Inkinen, A Mohammadi, MT Nieminen… - Scientific Reports, 2024 - nature.com
This proof-of-concept study explores quantitative imaging of articular cartilage using photon-
counting detector computed tomography (PCD-CT) with a dual-contrast agent approach …

Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints

J Quintiens, GH van Lenthe - Current Osteoporosis Reports, 2024 - Springer
Abstract Purpose of Review Recently, photon-counting computed tomography (PCCT) has
been introduced in clinical research and diagnostics. This review describes the …

[HTML][HTML] High-resolution synchrotron K-edge subtraction CT allows tracking and quantifying therapeutic cells and their scaffold in a rat model of focal cerebral injury …

C Tavakoli, E Cuccione, C Dumot, J Balegamire… - …, 2023 - ncbi.nlm.nih.gov
Background: The objective of this study was to demonstrate that synchrotron K-edge
subtraction tomography (SKES-CT) can simultaneously track therapeutic cells and their …

Revealing Detailed Cartilage Function Through Nanoparticle Diffusion Imaging: A Computed Tomography & Finite Element Study

J Tuppurainen, P Paakkari, J Jäntti… - Annals of Biomedical …, 2024 - Springer
The ability of articular cartilage to withstand significant mechanical stresses during activities,
such as walking or running, relies on its distinctive structure. Integrating detailed tissue …