The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament
initially characterized in neural stem cells. However, current extensive evidence obtained in …

Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …

The vimentin gene (VIM) encodes one of the 71 human intermediate filament (IF) proteins,
which are the building blocks of highly ordered, dynamic, and cell type-specific fiber …

Intermediate filaments constitute the third component of the cellular skeleton. Unlike actin
and microtubule cytoskeletons, the intermediate filaments are composed of a wide variety of …

Smooth muscle cell migration has been implicated in the development of respiratory and
cardiovascular systems; and airway/vascular remodeling. Cell migration is a polarized …

Intermediate filaments (IFs) are one of the three major elements of the cytoskeleton. Their
stability, intrinsic mechanical properties, and cell type–specific expression patterns …

The crucial role of cancer stem cells (CSC s) in the pathology of malignant diseases has
been extensively studied during the last decade. Nestin, a class VI intermediate filament …

The actin and intermediate filament cytoskeletons contribute to numerous cellular
processes, including morphogenesis, cytokinesis and migration. These two cytoskeletal …

Epithelial–mesenchymal transition (EMT) is recognized as a driving force of cancer cell
metastasis and drug resistance, two leading causes of cancer recurrence and cancer …

Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in
metazoans, and are traditionally known for their roles in fostering structural integrity in cells …