The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications

N Zhao, L Yan, X Zhao, X Chen, A Li, D Zheng… - Chemical …, 2018 - ACS Publications
Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …

Tumor targeting strategies of smart fluorescent nanoparticles and their applications in cancer diagnosis and treatment

J He, C Li, L Ding, Y Huang, X Yin, J Zhang… - Advanced …, 2019 - Wiley Online Library
Advantages such as strong signal strength, resistance to photobleaching, tunable
fluorescence emissions, high sensitivity, and biocompatibility are the driving forces for the …

Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis

J Chen, X Zhang, R Millican, J Sherwood… - Advanced drug delivery …, 2021 - Elsevier
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries,
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …

Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?

W Jeong, J Bu, LJ Kubiatowicz, SS Chen, YS Kim… - Nano …, 2018 - Springer
Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for
biomedical applications. Synergism between the two promising classes of materials allows …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Nanotechnology for cardiovascular diseases

Q Hu, Z Fang, J Ge, H Li - The Innovation, 2022 - cell.com
Cardiovascular diseases have become the major killers in today's world, among which
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …

Peptide‐Enabled Thrombus‐Targeting Nanoparticles for Highly Effective Targeted CT Imaging and Eradication of Thrombi

L Lu, Q Bao, Y Miao, Q Cheng, Y Chen… - Advanced Functional …, 2023 - Wiley Online Library
Thrombotic disease poses a significant threat to human health as it blocks blood vessels
and leads to severe symptoms. Effective treatment requires targeted therapy and precise …

Nanoparticle contrast agents for X‐ray imaging applications

JC Hsu, LM Nieves, O Betzer, T Sadan… - Wiley …, 2020 - Wiley Online Library
X‐ray imaging is the most widely used diagnostic imaging method in modern medicine and
several advanced forms of this technology have recently emerged. Iodinated molecules and …

Nanomedicine progress in thrombolytic therapy

A Zenych, L Fournier, C Chauvierre - Biomaterials, 2020 - Elsevier
Thrombotic occlusions of blood vessels are responsible for life-threatening cardiovascular
disorders such as myocardial infarction, ischemic stroke, and venous thromboembolism …