Lipid metabolism in cancer progression and therapeutic strategies
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …
Ceramide synthase CERS4 gene downregulation is associated with KRAS mutation in colorectal cancer
T Hayama, K Hama, T Ozawa, Y Fujiwara, K Nozawa… - Scientific Reports, 2023 - nature.com
Ceramide, the central molecule in sphingolipid synthesis, is a bioactive lipid that serves as a
regulatory molecule in the anti-inflammatory responses, apoptosis, programmed necrosis …
regulatory molecule in the anti-inflammatory responses, apoptosis, programmed necrosis …
Ceramide synthases: insights into the expression and prognosis of lung cancer
H Qian, J Deng, C Lu, G Hou, H Zhang… - Experimental Lung …, 2021 - Taylor & Francis
CerSs (ceramide synthases), a group of enzymes that catalyze the formation of ceramides
from sphingoid base and acyl-CoA substrates. As far, six types of CerSs (CerS1-CerS6) …
from sphingoid base and acyl-CoA substrates. As far, six types of CerSs (CerS1-CerS6) …
[HTML][HTML] High expression of ceramide synthase 5 predicts a poor prognosis in gastric cancer
S Zhang, Y Wang, L Yuan, C Hu, Z Xu… - Translational Cancer …, 2022 - ncbi.nlm.nih.gov
Background Gastric cancer is one of the most common malignant tumors worldwide.
Ceramide synthase 5 (CerS5) is a member of the CerS family. Emerging evidence has …
Ceramide synthase 5 (CerS5) is a member of the CerS family. Emerging evidence has …
[HTML][HTML] C16: 0 ceramide effect on melanoma malignant behavior and glycolysis depends on its intracellular or exogenous location
R Liu, K Cao, Y Tang, J Liu, J Li, J Chen… - American Journal of …, 2020 - ncbi.nlm.nih.gov
To investigate the role of C16: 0 ceramide in melanoma metastatic behavior and glycolysis,
five common long-chain ceramides (C16: 0, C18: 0, C20: 0, C22: 0, C24: 0) were tested in …
five common long-chain ceramides (C16: 0, C18: 0, C20: 0, C22: 0, C24: 0) were tested in …