[HTML][HTML] Outlook of PINK1/Parkin signaling in molecular etiology of Parkinson's disease, with insights into Pink1 knockout models
Z Wang, SW Chan, H Zhao, KK Miu… - Zoological …, 2023 - ncbi.nlm.nih.gov
Parkinson's disease (PD) relates to defective mitochondrial quality control in the
dopaminergic motor network. Genetic studies have revealed that PINK1 and Parkin …
dopaminergic motor network. Genetic studies have revealed that PINK1 and Parkin …
The role of mtDNA in oocyte quality and embryo development
The mitochondrial genome resides in the mitochondria present in nearly all cell types. The
porcine (Sus scrofa) mitochondrial genome is circa 16.7 kb in size and exists in the …
porcine (Sus scrofa) mitochondrial genome is circa 16.7 kb in size and exists in the …
Age-associated global DNA hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury
SR Boovarahan, N Ali, AF AlAsmari, AA Alameen… - Frontiers in …, 2022 - frontiersin.org
Most pre-clinical studies in cardiac ischemia-reperfusion injury (I/R) are carried out in young
or old animals, which does not cater to the adult age in humans who encounter I/R. Not …
or old animals, which does not cater to the adult age in humans who encounter I/R. Not …
[HTML][HTML] Rewiring of IGF1 secretion and enhanced IGF1R signaling induced by co-chaperone carboxyl-terminus of Hsp70 interacting protein in adipose-derived stem …
Aging-associated cardiovascular diseases depend on the longitudinal deterioration of stem
cell dynamics. The entire mechanism behind it is not completely understood. However …
cell dynamics. The entire mechanism behind it is not completely understood. However …
[HTML][HTML] DNA polymerase gamma recovers mitochondrial function and inhibits vascular calcification by interacted with p53
P Wang, B Wu, S You, S Lu, S Xiong… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
DNA polymerase gamma (PolG) is the major polymerase of mitochondrial DNA (mtDNA)
and essential for stabilizing mitochondrial function. Vascular calcification (VC) is common …
and essential for stabilizing mitochondrial function. Vascular calcification (VC) is common …