LA Kasatkina, S Rittchen, EM Sturm - International Journal of Molecular …, 2021 - mdpi.com
Endocannabinoids (eCBs) are lipid-based retrograde messengers with a relatively short half- life that are produced endogenously and, upon binding to the primary cannabinoid receptors …
Background: Anacardium occidentale L. is a medicinal plant with powerful anti-oxidative and anti-inflammatory properties. Acute inflammatory events cause tissue alterations, decrease …
D Impellizzeri, R D'Amico, R Fusco, T Genovese… - Cells, 2022 - mdpi.com
The second-most common cause of dementia is vascular dementia (VaD). The majority of VaD patients experience cognitive impairment, which is brought on by oxidative stress and …
Alzheimer's disease (AD) is the principal cause of dementia, and its incidence increases with age. Altered antioxidant systems and inflammation have an important role in the …
Osteoarthritis is a progressive joint disease characterized by the activation of different molecular mediators, including proinflammatory cytokines, reactive oxygen species …
R D'Amico, D Impellizzeri, S Cuzzocrea… - International journal of …, 2020 - mdpi.com
Neuropathic pain results from lesions or diseases of the somatosensory nervous system and it remains largely difficult to treat. Peripheral neuropathic pain originates from injury to the …
D Impellizzeri, AF Peritore, M Cordaro… - The FASEB …, 2019 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is a complication of diabetes connected with morbidity and mortality. DPN presents deterioration of peripheral nerves with pain …
R D'Amico, D Impellizzeri, T Genovese, R Fusco… - Molecular …, 2022 - Springer
The current pharmacological treatment for Parkinson's disease (PD) is focused on symptom alleviation rather than disease prevention. In this study, we look at a new strategy to …
Vascular dementia (VaD) is the second leading cause of dementia. The majority of VaD patients have cognitive abnormalities, which are caused by cerebral hypoperfusion-induced …