In the late 70's, the discovery of the restriction enzymes made possible the biological
production of functional proteins by recombinant DNA technologies, a fact that largely …

We have developed a simple, robust, and fully transversal approach for the a-la-carte
fabrication of functional multimeric nanoparticles with potential biomedical applications …

Fatty liver is considered to be the most common chronic liver disease with a high global
incidence, which can lead to cirrhosis and liver cancer in severe cases, and there is no …

Advanced medical treatments involving drug delivery require fully biocompatible materials
with the ability to release functional drugs in a time‐prolonged way. Ideally, the delivered …

The coordination between histidine-rich peptides and divalent cations supports the
formation of nano-and micro-scale protein biomaterials, including toxic and non-toxic …

The possibility to conjugate tumor-targeted cytotoxic nanoparticles and conventional
antitumoral drugs in single pharmacological entities would open a wide spectrum of …

A functional 29 amino acid-segment of the helix α5 from the human BAX protein has been
engineered for production in recombinant bacteria as self-assembling, GFP-containing …

The need for more effective and precision medicines for cancer has pushed the exploration
of new materials appropriate for drug delivery and imaging, and alternative receptors for …

Poly-histidine peptides such as H6 (HHHHHH) are used in protein biotechnologies as
purification tags, protein-assembling agents and endosomal-escape entities. The pleiotropic …

Five peptide ligands of four different cell surface receptors (nucleolin, CXCR1, CMKLR1,
and CD44v6) have been evaluated as targeting moieties for triple-negative human breast …