Organic Bioelectronics for In Vitro Systems

C Pitsalidis, AM Pappa, AJ Boys, Y Fu… - Chemical …, 2021 - ACS Publications
Bioelectronics have made strides in improving clinical diagnostics and precision medicine.
The potential of bioelectronics for bidirectional interfacing with biology through continuous …

Next-generation probes, particles, and proteins for neural interfacing

J Rivnay, H Wang, L Fenno, K Deisseroth… - Science …, 2017 - science.org
Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …

Organic bioelectronics: from functional materials to next‐generation devices and power sources

D Ohayon, S Inal - Advanced Materials, 2020 - Wiley Online Library
Conjugated polymers (CPs) possess a unique set of features setting them apart from other
materials. These properties make them ideal when interfacing the biological world …

Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy

JF Maya-Vetencourt, G Manfredi, M Mete… - Nature …, 2020 - nature.com
Inherited retinal dystrophies and late-stage age-related macular degeneration, for which
treatments remain limited, are among the most prevalent causes of legal blindness. Retinal …

Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities

Y Huang, Y Cui, H Deng, J Wang, R Hong… - Nature Biomedical …, 2023 - nature.com
Neural activities can be modulated by leveraging light-responsive nanomaterials as
interfaces for exerting photothermal, photoelectrochemical or photocapacitive effects on …

A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness

JF Maya-Vetencourt, D Ghezzi, MR Antognazza… - Nature materials, 2017 - nature.com
The degeneration of photoreceptors in the retina is one of the major causes of adult
blindness in humans. Unfortunately, no effective clinical treatments exist for the majority of …

Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas

NAL Chenais, MJI Airaghi Leccardi… - Communications …, 2021 - nature.com
Retinal prostheses hold the promise of restoring vision in totally blind people. However, a
decade of clinical trials highlighted quantitative limitations hampering the possibility of …

Neural modulation with photothermally active nanomaterials

Y Wang, R Garg, D Cohen-Karni… - Nature Reviews …, 2023 - nature.com
Modulating neural electrophysiology with high precision is essential for understanding
neural communication and for the diagnosis and treatment of neural disorders. Photothermal …

Neuronal firing modulation by a membrane-targeted photoswitch

ML DiFrancesco, F Lodola, E Colombo… - Nature …, 2020 - nature.com
Optical technologies allowing modulation of neuronal activity at high spatio-temporal
resolution are becoming paramount in neuroscience. In this respect, azobenzene-based …

Organic bioelectronics: using highly conjugated polymers to interface with biomolecules, cells, and tissues in the human body

SG Higgins, A Lo Fiego, I Patrick… - Advanced Materials …, 2020 - Wiley Online Library
Conjugated polymers exhibit interesting material and optoelectronic properties that make
them well‐suited to the development of biointerfaces. Their biologically relevant mechanical …