Distraction osteogenesis (DO) is widely used for bone tissue engineering technology.
Immune regulations play important roles in the process of DO like other bone regeneration …

The regulation of organ size is essential to human health and has fascinated biologists for
centuries. Key to the growth process is the ability of most organs to integrate organ-extrinsic …

Osteoporosis is a major health problem, making bones fragile and susceptible to fracture.
Previous works showed that mechanical loading stimulated bone formation and accelerated …

Infected nonunions of tibia pose many challenges to the treating surgeon and the patient.
Challenges include recalcitrant infection, complex deformities, sclerotic bone ends, large …

Background: The concept of reverse dynamization involves modifying the mechanical
environment surrounding a fracture to influence the healing response. Initially, less rigid …

Distraction osteogenesis (DO) is a mechanobiological process of regenerating bone tissue
by tension stress. DO is used clinically to lengthen bones or to treat critical size bone …

Distraction osteogenesis (DO) is a valuable surgical method for limb lengthening and bone
defect correction, but its lengthy consolidation phase presents challenges. The accordion …

Distraction osteogenesis biologically resembles fracture healing with distinctive
characteristics notably in the distraction phase of osteogenesis. In the latency phase of bone …

Mechanical unloading was considered a major threat to bone homeostasis, and has been
shown to decrease osteoblast proliferation although the underlying mechanism is unclear …

Introduction Ilizarov bone transport for large bone defect is challenging and may end in
distraction osteogenesis failure. Material and methods Ten forearm and seven tibial defect …