Medial arterial calcification (MAC) is a chronic systemic vascular disorder distinct from
atherosclerosis that is frequently but not always associated with diabetes mellitus, chronic …

A significant proportion of lesions treated with transcatheter interventions in the coronary
and peripheral vascular beds exhibit moderate to severe calcific plaques known to portend …

Background Coronary calcification hinders stent delivery and expansion and is associated
with adverse outcomes. Intravascular lithotripsy (IVL) delivers acoustic pressure waves to …

Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients≥ 80
years of age. Nonetheless, older patients have typically been under-represented in …

Rotational atherectomy (RA) is an established tool in interventional cardiology for treatment
of calcified coronary lesions. Over 3 decades of clinical experience and research …

Background: Balloon dilatation or debulking seems to be essential to allow successful stent
implantation in calcified coronary lesions. Compared with standard balloon predilatation …

Patients with obstructive coronary lesions with a high calcium content (LHCC) have an
exaggerated clinical risk, because the presence of calcification is associated with more …

The cardiovascular science community has pursued the quest to identify vulnerable
atherosclerotic plaque in patients for decades, hoping to prevent acute coronary events …

While coronary angiography is the gold standard diagnostic tool for coronary artery disease
(CAD), but it is associated with procedural risk, it is an invasive technique requiring arterial …

Objectives The aim of this pooled analysis was to assess the cumulative safety and
effectiveness of coronary intravascular lithotripsy (IVL). Background The clinical outcomes of …