Type 1 diabetes (T1D) is an autoimmune disease caused by the immune system attacking
and destroying insulin-producing β cells in the pancreas. Islet transplantation is becoming …

Clinical islet transplantation has the potential to cure type 1 diabetes. Despite recent
therapeutic success, it is still uncommon because transplanted islets are damaged by …

Upon contact with biological fluids like serum, a protein corona (PC) complex forms on iron
oxide nanoparticles (IONPs) in physiological environments and the proteins it contains …

The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine
protease cascades are critical determinants of morbidity and mortality during infection and …

As a newly emerging organ transplantation technique, islet transplantation has shown the
advantages of minimal trauma and high safety since it was first carried out. The proposal of …

Islet/β-cell transplantation offers great hope for patients with type 1 diabetes. We assessed
the mechanisms of how intrahepatic coinfusion of human α-1 antitrypsin (hAAT)-engineered …

End-stage organ failure often requires solid organ transplantation. Nevertheless, transplant
rejection remains an unresolved issue. The induction of donor-specific tolerance is the …

Endometriosis is characterized by the presence of inflamed and fibrotic endometrial tissue
outside the uterine cavity. Previously, we found decreased SERPINA1 (alpha-1 antitrypsin) …

Islet transplantation to treat the late stage of type 1 diabetic patient (T1DM) has recently
made inspiring success in clinical trials. However, most patients experience a decline in islet …

Corneal lymphangiogenesis induced by macrophages played a critical role in corneal
allograft rejection (CGR). However, there are few Food and Drug Administration (FDA) …