Neutrophils are critical to innate immunity, including host defense against bacterial and
fungal infections. They achieve their host defense role by phagocytosing pathogens …

The epigenetic modifications of histones are versatile marks that are intimately connected to
development and disease pathogenesis including human cancers. In this review, we will …

Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Histone posttranslational modifications represent a versatile set of epigenetic marks
involved not only in dynamic cellular processes, such as transcription and DNA repair, but …

Neutrophils dominate the early immune response in pathogen-induced acute lung injury, but
efforts to harness their responses have not led to therapeutic advancements. Neutrophil …

Neutrophils are essential to the homeostatic mission of safeguarding host tissues,
responding rapidly and diversely to breaches of the host's barriers to infection, and returning …

Post-translational modification (PTM) of proteins is vital for increasing proteome diversity
and maintaining cellular homeostasis. If the writing, reading, and removal of modifications …

Post-translational modifications of histone proteins and exchanges of histone variants of
chromatin are central to the regulation of nearly all DNA-templated biological processes …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

Perturbations in lipid homeostasis combined with conditions favoring oxidative stress
constitute a hallmark of the inflammatory response. In this review we focus on the most …