Does U= U for breastfeeding mothers and infants? Breastfeeding by mothers on effective treatment for HIV infection in high-income settings
Summary Can the campaign Undetectable= Untransmittable (U= U), established for the
sexual transmission of HIV, be applied to the transmission of HIV through breastfeeding …
sexual transmission of HIV, be applied to the transmission of HIV through breastfeeding …
Transmission of CMV, HTLV-1, and HIV through breastmilk
AJ Prendergast, AE Goga, C Waitt… - The Lancet Child & …, 2019 - thelancet.com
Breastfeeding is a crucial child survival intervention. However, the potential for transmission
of viral infections from mother to child presents the dilemma of how best to interpret the …
of viral infections from mother to child presents the dilemma of how best to interpret the …
Characterization of nanodiamond-based anti-HIV drug delivery to the brain
Abstract Human Immunodeficiency Virus Type 1 (HIV-1) remains one of the leading causes
of death worldwide. Present combination antiretroviral therapy has substantially improved …
of death worldwide. Present combination antiretroviral therapy has substantially improved …
Optimizing pharmacology studies in pregnant and lactating women using lessons from HIV: a consensus statement
AC Eke, A Olagunju, J Momper… - Clinical …, 2021 - Wiley Online Library
Information on the extent of drug exposure to mothers and infants during pregnancy and
lactation normally becomes available years after regulatory approval of a drug. Clinicians …
lactation normally becomes available years after regulatory approval of a drug. Clinicians …
[HTML][HTML] African Pharmacogenomics Consortium: consolidating pharmacogenomics knowledge, capacity development and translation in Africa: consolidating …
Abstract The African Pharmacogenomics Consortium (APC) was formally launched on the
6th September 2018. This white paper outlines its vision, and objectives towards addressing …
6th September 2018. This white paper outlines its vision, and objectives towards addressing …
A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases
Background Exclusive breastfeeding of infants under 6 months of age is recommended by
the World Health Organization. In 2021, over 300 million combined incident cases of …
the World Health Organization. In 2021, over 300 million combined incident cases of …
Plasma and breast milk pharmacokinetics of emtricitabine, tenofovir and lamivudine using dried blood and breast milk spots in nursing African mother–infant pairs
Background Breast milk transfer of first-line ART from mother to infant is not fully understood.
Objectives To determine the concentrations of lamivudine, emtricitabine and tenofovir in …
Objectives To determine the concentrations of lamivudine, emtricitabine and tenofovir in …
Physiologically based pharmacokinetic modeling to determine the impact of CYP2B6 genotype on efavirenz exposure in children, mothers and breastfeeding infants
X Pan, K Rowland Yeo - Clinical Pharmacology & Therapeutics, 2023 - Wiley Online Library
The antiretroviral drug efavirenz remains widely used in children and mothers during
breastfeeding in tuberculosis‐endemic areas. Evaluating the safety of efavirenz during …
breastfeeding in tuberculosis‐endemic areas. Evaluating the safety of efavirenz during …
Distribution evaluation of tenofovir in the breast milk of mothers with HBeAg-positive chronic HBV infection after treatment with tenofovir alafenamide and tenofovir …
N Yang, G Zhou, X Cheng, J He, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir (TFV) that has been approved
for the treatment of chronic hepatitis B virus (HBV) infection. It has greater plasma stability …
for the treatment of chronic hepatitis B virus (HBV) infection. It has greater plasma stability …
Associations between efavirenz concentrations, pharmacogenetics and neurocognitive performance in people living with HIV in Nigeria
Objective: Efavirenz (EFV) use is associated with neuropsychiatric side effects, which may
include poor neurocognitive performance. We evaluated single nucleotide polymorphisms in …
include poor neurocognitive performance. We evaluated single nucleotide polymorphisms in …