Conserved protein kinases with core cellular functions have been frequently redeployed
during metazoan evolution to regulate specialized developmental processes. The Ser/Arg …

Background Inhaled corticosteroids (ICS) are the most widely prescribed and effective
medication to control asthma symptoms and exacerbations. However, many children still …

Recent genome-wide association studies have successfully identified associations between
genetic variants and simple cardiac morphological parameters derived from cardiac …

Background: The type X collagen gene (Col10a1) is a signature gene of hypertrophic
chondrocytes that are known as the main engine of long bone growth. Multiple transcription …

The cranial vault in humans is highly variable, clinically relevant, and heritable, yet its
genetic architecture remains poorly understood. Here, we conduct a joint multi-ancestry and …

Craniofacial development requires precise spatiotemporal regulation of multiple signaling
pathways that crosstalk to coordinate the growth and patterning of the skull with surrounding …

(1) Background: anthropometric measurements with calipers are used to objectify cranial
asymmetry in positional plagiocephaly but there is controversy regarding the reliability of …

This study assessed the regional diversity of the human cranial form by using geometric
homologous models based on scanned data from 148 ethnic groups worldwide. This …

As one of the most common types of osteoporosis, postmenopausal osteoporosis (PMOP) is
caused by both genetic and environmental factors. Previous studies have indicated that …

Context A hypothesis-free genetic association analysis has not been reported for patients
with primary hyperparathyroidism (PHPT). Objective We aimed to investigate genetic …