[HTML][HTML] Engineering topography: Effects on corneal cell behavior and integration into corneal tissue engineering

S Xiong, HC Gao, L Qin, YG Jia, L Ren - Bioactive materials, 2019 - Elsevier
Cell-material interactions are important to tissue engineering. Inspired by the natural
topographic structures on the extracellular matrix, a growing number of studies have …

Concise reviews: the role of biomechanics in the limbal stem cell niche: new insights for our understanding of this structure

P Eberwein, T Reinhard - Stem Cells, 2015 - academic.oup.com
The limbal stem cell niche is a structure of the ocular surface that is characterized by high
specification, organization, and clinical significance. Harboring the limbal epithelial stem …

[HTML][HTML] Modulation of focal adhesion constituents and their down-stream events by EGF: On the cross-talk of integrins and growth factor receptors

P Eberwein, D Laird, S Schulz, T Reinhard… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Within the concept of integrin growth factor receptor (GFR) cross-talk, little is known about
the effects of GFRs on focal adhesions (FAs). Therefore, we tested the hypothesis whether …

Rose petal topography mimicked poly (dimethylsiloxane) substrates for enhanced corneal endothelial cell behavior

MÖ Öztürk-Öncel, FZ Erkoc-Biradli, R Rasier… - Materials Science and …, 2021 - Elsevier
Low proliferation capacity of corneal endothelial cells (CECs) and worldwide limitations in
transplantable donor tissues reveal the critical need of a robust approach for in vitro CEC …

Nanofibered gelatin‐based nonwoven elasticity promotes epithelial Histogenesis

N Jedrusik, C Meyen, G Finkenzeller… - Advanced …, 2018 - Wiley Online Library
Regarding tissue regeneration, mechanics of biomaterials gains progressive importance.
Therefore, this study reports on in situ crosslinked electrospun gelatin nonwoven mats …

A simple basis for determination of the modulus and hydraulic conductivity of human ocular surface using nano-indentation

MV Swain, J Nohava, P Eberwein - Acta biomaterialia, 2017 - Elsevier
This paper presents a simple analysis based upon Darcy's Law and indentation contact
mechanics to determine the effective hydraulic conductivity and elastic modulus of fluid filled …

Substrate elasticity as biomechanical modulator of tissue homeostatic parameters in corneal keratinocytes

K Moers, T Steinberg, G Schlunck, T Reinhard… - Experimental cell …, 2013 - Elsevier
This study aimed at identifying putative modulations of tissue homeostatic parameters in
corneal keratinocytes in response to biomechanical cues as basis for innovative cornea …

[PDF][PDF] Modulation of gingival cell response towards dental composites

A Jerg, SD Schulz, P Tomakidi, E Hellwig… - Dental …, 2018 - researchgate.net
abstract Objective. This aim of this study was to investigate the cell behavioural response on
clinically applied dental composites in exposition-relevant target cells, ie human gingival …

3D microfabricated scaffolds and microfluidic devices for ocular surface replacement: a review

E Prina, P Mistry, LE Sidney, J Yang… - Stem Cell Reviews and …, 2017 - Springer
In recent years, there has been increased research interest in generating corneal
substitutes, either for use in the clinic or as in vitro corneal models. The advancement of 3D …

Bioinspired precision engineering of three‐dimensional epithelial stem cell microniches

E Prina, MH Amer, L Sidney, M Tromayer… - Advanced …, 2020 - Wiley Online Library
Maintenance of the epithelium relies on stem cells residing within specialized
microenvironments, known as epithelial crypts. Two‐photon polymerization (2PP) is a …