Cancer cell migration and invasion underlie metastatic dissemination, one of the major
problems in cancer. Tumour cells exhibit a striking variety of invasion strategies. Importantly …

Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …

Macrophages are recruited into the cochlea in response to injury caused by acoustic trauma
or ototoxicity, but the nature of the interaction between macrophages and the sensory …

Integrating signals from multiple receptors allows cells to interpret the physiological context
in which a signal is received. Here we describe a mechanism for receptor crosstalk in which …

Hepatocellular carcinoma (HCC) is a prevalent malignant tumor worldwide, with an
unsatisfactory prognosis, although treatments are improving. One of the main challenges for …

Cochlear hair cells are vulnerable to a variety of insults like acoustic trauma and ototoxic
drugs. Such injury can also lead to degeneration of spiral ganglion neurons (SGNs), but this …

The chemotactic cytokine fractalkine (FKN, chemokine CX3CL1) has unique properties
resulting from the combination of chemoattractants and adhesion molecules. The soluble …

Abstract Spinal metastasis occurs in 50‑75% of bone metastases caused by hepatocellular
carcinoma (HCC), and HCC‑derived spinal metastasis can lead to a less favorable …

Pneumonia and inflammatory diseases of the pulmonary system such as chronic obstructive
pulmonary disease and asthma continue to cause significant morbidity and mortality …

The most replicated neuroanatomical finding in autism is the tendency toward brain
overgrowth, especially in younger children. Research shows that both gray and white matter …