Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

Y Jiang, Y Chen, Z Song, Z Tan, J Cheng - Advanced Drug Delivery …, 2021 - Elsevier
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Membrane active antimicrobial peptides: translating mechanistic insights to design

J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …

Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

Antimicrobial peptides

AA Bahar, D Ren - Pharmaceuticals, 2013 - mdpi.com
The rapid increase in drug-resistant infections has presented a serious challenge to
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …

Nano-structured antimicrobial surfaces: From nature to synthetic analogues

A Elbourne, RJ Crawford, EP Ivanova - Journal of Colloid and Interface …, 2017 - Elsevier
The scientific and industrial interest in antimicrobial surfaces has significantly increased in
recent times. This interest is largely in response to the persistent microbial contamination of …

Computer-aided design of antimicrobial peptides: are we generating effective drug candidates?

MH Cardoso, RQ Orozco, SB Rezende… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely
investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally …

Breakthroughs in bacterial resistance mechanisms and the potential ways to combat them

B Khameneh, R Diab, K Ghazvini, BSF Bazzaz - Microbial pathogenesis, 2016 - Elsevier
Multidrug-resistant (MDR) bacteria have increased at an alarming rate over recent decades
and cause serious problems. The emergence of resistant infections caused by these …

Polymeric materials with antimicrobial activity

A Muñoz-Bonilla, M Fernández-García - Progress in Polymer Science, 2012 - Elsevier
This article describes the state of the art in the field of antimicrobial polymeric systems during
the last decade. Keeping in mind the multitude of existing systems, a classification of the …

[HTML][HTML] Antimicrobial polymers in solution and on surfaces: overview and functional principles

F Siedenbiedel, JC Tiller - Polymers, 2012 - mdpi.com
The control of microbial infections is a very important issue in modern society. In general
there are two ways to stop microbes from infecting humans or deteriorating materials …

Engineering precise sequence-defined polymers for advanced functions

Q Shi, Z Deng, M Hou, X Hu, S Liu - Progress in Polymer Science, 2023 - Elsevier
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …