Sirtuins are a class of NAD+-dependent deacetylases having beneficial health effects. This
extensive review describes the numerous intracellular actions of the seven mammalian …

Sirtuins are a highly conserved family of nicotinamide adenine dinucleotide (NAD+)-
dependent protein lysine modifying enzymes with deacetylase, adenosine …

The selection of liver transplant candidates with hepatocellular carcinoma (HCC) relies
mostly on tumor size and number. Instead of relying on these factors, we used poor tumor …

Background Although depression is the leading cause of disability worldwide, its
pathophysiology is poorly understood. Recent evidence has suggested that sirtuins (SIRTs) …

Reports of the bone‐protective effects of resveratrol, a naturally occurring phytoestrogen and
agonist for the longevity gene SIRT1, have highlighted this compound as a candidate for …

Abstract The Forkhead box O (FoxO) family has recently been highlighted as an important
transcriptional regulator of crucial proteins associated with the many diverse functions of …

Strategies that increase homing to the bone marrow and engraftment efficacy of ex vivo
expended CD34+ cells are expected to enhance their clinical utility. Here we report that …

Dry eye disease is a prevalent eye disorder that in particular affects the elderly population.
One of the major causes of dry eye, meibomian gland dysfunction (MGD), shows increased …

The mammalian nicotinamide‐adenine dinucleotide (NAD)‐dependent deacetylase Sirt1
impacts different processes involved in the maintenance of brain integrity and in the …

Autophagy is a fundamental cellular process that eliminates long-lived proteins and
damaged organelles through lysosomal degradation pathway. Cigarette smoke (CS) …