Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …

Decellularized extracellular matrix (dECM) is a promising biomaterial for repairing
cardiovascular tissue, as dECM most effectively captures the complex array of proteins …

A variety of decellularized materials have been developed that have demonstrated potential
for treating cardiovascular diseases and improving our understanding of cardiac …

Biologic scaffolds composed of extracellular matrix (ECM) are frequently used for clinical
purposes of tissue regeneration. Different methods have been developed for this purpose …

Irreversible end-stage organ failure represents one of the leading causes of death, and
organ transplantation is currently the only curative solution. Donor organ shortage and …

OBJECTIVES One of the final treatments for end-stage heart failure is heart transplantation.
However, a shortage of donor hearts has created a long waiting list and limited benefits. Our …

Thrombosis associated with medical devices may lead to dramatic increases in morbidity,
mortality and increased health care costs. Innovative strategies are being developed to …

Heart failure is the leading cause of death in the United States and rapidly becoming the
leading cause of death worldwide. While pharmacological treatments can reduce …

Despite all the advances in preventing, diagnosing, and treating cardiovascular disorders,
they still account for a significant part of mortality and morbidity worldwide. The advent of …