The influence of microbiota on host health and disease has attracted adequate attention,
and gut microbiota components and microbiota-derived metabolites affect host immune …

Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

The discovery void of antimicrobial development has occurred at a time when the world has
seen a rapid emergence and spread of antimicrobial resistance, the 'perfect storm'as it has …

Background Microbial communities are known to be closely related to many diseases, such
as obesity and HIV, and it is of interest to identify differentially abundant microbial species …

METHODS: We prospectively recruited lung transplant (LTX) patients and nontransplant
patients with respiratory symptoms (RP) and collected paired gastric and lung samples. Bile …

Abstract Background Cystic Fibrosis (CF) is a genetic condition characterized by neutrophilic
inflammation and recurrent infection of the airways. How these processes are initiated and …

Cystic fibrosis (CF) is a multisystem genetic disease which affects numerous organs in the
body. Patients with CF exhibit profound alterations in the gastrointestinal microbiome …

The advent of next generation sequencing has rapidly challenged the paediatric respiratory
physician's understanding of lung microbiology and the role of the lung microbiome in host …

Gastroesophageal reflux (GER) occurs in most cystic fibrosis (CF) patients and is the primary
source of bile aspiration in the airway tract of CF individuals. Aspirated bile is associated …