Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability

M Boretto, B Cox, M Noben, N Hendriks… - …, 2017 - journals.biologists.com
The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …

Inflammation and pregnancy: the role of the immune system at the implantation site

G Mor, I Cardenas, V Abrahams… - Annals of the new York …, 2011 - Wiley Online Library
The concept that pregnancy is associated with immune suppression has created a myth of
pregnancy as a state of immunological weakness and, therefore, of increased susceptibility …

Embryo implantation evolved from an ancestral inflammatory attachment reaction

OW Griffith, AR Chavan, S Protopapas… - Proceedings of the …, 2017 - National Acad Sciences
The molecular changes that support implantation in eutherian mammals are necessary to
establish pregnancy. In marsupials, pregnancy is relatively short, and although a placenta …

Endometrial exosomes/microvesicles in the uterine microenvironment: a new paradigm for embryo-endometrial cross talk at implantation

YH Ng, S Rome, A Jalabert, A Forterre, H Singh… - PloS one, 2013 - journals.plos.org
Exosomes are nanoparticles (∼ 100 nm diameter) released from cells, which can transfer
small RNAs and mRNA via the extracellular environment to cells at distant sites. We …

Endometrial receptivity markers, the journey to successful embryo implantation

H Achache, A Revel - Human reproduction update, 2006 - academic.oup.com
Human embryo implantation is a three-stage process (apposition, adhesion and invasion)
involving synchronized crosstalk between a receptive endometrium and a functional …

Molecular cues to implantation

SK Dey, H Lim, SK Das, J Reese, BC Paria… - Endocrine …, 2004 - academic.oup.com
Successful implantation is the result of reciprocal interactions between the implantation-
competent blastocyst and receptive uterus. Although various cellular aspects and molecular …

Embryo–epithelium interactions during implantation at a glance

JD Aplin, PT Ruane - Journal of cell science, 2017 - journals.biologists.com
At implantation, with the acquisition of a receptive phenotype in the uterine epithelium, an
initial tenuous attachment of embryonic trophectoderm initiates reorganisation of epithelial …

Embryonic implantation: cytokines, adhesion molecules, and immune cells in establishing an implantation environment

MSM Van Mourik, NS Macklon… - Journal of Leucocyte …, 2009 - academic.oup.com
Successful implantation is an absolute requirement for the reproduction of species, including
humans. The process by which a foreign blastocyst is accepted by the maternal …