[HTML][HTML] The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple …

P Sati, J Oh, RT Constable, N Evangelou… - Nature Reviews …, 2016 - nature.com
Over the past few years, MRI has become an indispensable tool for diagnosing multiple
sclerosis (MS). However, the current MRI criteria for MS diagnosis have imperfect sensitivity …

Imaging chronic active lesions in multiple sclerosis: a consensus statement

F Bagnato, P Sati, CC Hemond, C Elliott, SA Gauthier… - Brain, 2024 - academic.oup.com
Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …

Voxel spread function method for correction of magnetic field inhomogeneity effects in quantitative gradient‐echo‐based MRI

DA Yablonskiy, AL Sukstanskii, J Luo… - Magnetic resonance in …, 2013 - Wiley Online Library
Purpose Macroscopic magnetic field inhomogeneities adversely affect different aspects of
MRI images. In quantitative MRI when the goal is to quantify biological tissue parameters …

Rapid, high-resolution, whole-brain, susceptibility-based MRI of multiple sclerosis

P Sati, DM Thomasson, N Li, DL Pham… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Susceptibility-based MRI offers a unique opportunity to study neurological
diseases such as multiple sclerosis (MS). In this work, we assessed a three-dimensional …

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

G Bonnier, A Roche, D Romascano… - Annals of clinical …, 2014 - Wiley Online Library
Introduction In patients with multiple sclerosis (MS), conventional magnetic resonance
imaging (MRI) provides only limited insights into the nature of brain damage with modest …

In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging

Y Zhao, ME Raichle, J Wen, TL Benzinger, AM Fagan… - Neuroimage, 2017 - Elsevier
Background Alzheimer disease (AD) affects at least 5 million individuals in the USA alone
stimulating an intense search for disease prevention and treatment therapies as well as for …

Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis

DA Yablonskiy, J Luo, AL Sukstanskii… - Proceedings of the …, 2012 - National Acad Sciences
Phase images obtained with gradient echo MRI provide image contrast distinct from T1-and
T2-weighted images. It is commonly assumed that the local contribution to MRI signal phase …

On the role of physiological fluctuations in quantitative gradient echo MRI: implications for GEPCI, QSM, and SWI

J Wen, AH Cross, DA Yablonskiy - Magnetic resonance in …, 2015 - Wiley Online Library
Purpose Physiological fluctuations in biological tissues adversely affect MR images if
present during signal acquisition. This problem is especially important for quantitative MRI …

In vivo quantification of T2⁎ anisotropy in white matter fibers in marmoset monkeys

P Sati, AC Silva, P van Gelderen, MI Gaitan, JE Wohler… - Neuroimage, 2012 - Elsevier
T2⁎-weighted MRI at high field is a promising approach for studying noninvasively the
tissue structure and composition of the brain. However, the biophysical origin of T2⁎ …

Gradient echo plural contrast imaging—signal model and derived contrasts: T2*, T1, phase, SWI, T1f, FST2* and T2*-SWI

J Luo, BD Jagadeesan, AH Cross, DA Yablonskiy - Neuroimage, 2012 - Elsevier
Gradient Echo Plural Contrast Imaging (GEPCI) is a post processing technique that, based
on a widely available multiple gradient echo sequence, allows simultaneous generation of …