Chikungunya virus infection: molecular biology, clinical characteristics, and epidemiology in Asian countries

S Khongwichit, J Chansaenroj, C Chirathaworn… - Journal of Biomedical …, 2021 - Springer
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne human pathogen that causes
chikungunya fever, which is typically accompanied by severe joint pain. In Asia, serological …

Cellular attachment and entry factors for chikungunya virus

BS Schnierle - Viruses, 2019 - mdpi.com
Chikungunya virus (CHIKV) is clinically the most relevant member of the Alphavirus genus.
Like alphaviruses in general, CHIKV has the capacity to infect a large variety of cells …

The effect of amantadine on an ion channel protein from Chikungunya virus

D Dey, SI Siddiqui, P Mamidi, S Ghosh… - PLoS neglected …, 2019 - journals.plos.org
Viroporins like influenza A virus M2, hepatitis C virus p7, HIV-1 Vpu and picornavirus 2B
associate with host membranes, and create hydrophilic corridors, which are critical for viral …

Chikungunya vaccines in development

M Schwameis, N Buchtele, PP Wadowski… - Human vaccines & …, 2016 - Taylor & Francis
Chikungunya virus has become a global health threat, spreading to the industrial world of
Europe and the Americas; no treatment or prophylactic vaccine is available. Since the late …

The interplay of viral and host factors in chikungunya virus infection: targets for antiviral strategies

KZ Wong, JJH Chu - Viruses, 2018 - mdpi.com
Chikungunya virus (CHIKV) has re-emerged as one of the many medically important
arboviruses that have spread rampantly across the world in the past decade. Infected …

Sphingosine kinase 2 is a chikungunya virus host factor co-localized with the viral replication complex

SP Reid, SR Tritsch, K Kota, CY Chiang… - Emerging microbes & …, 2015 - Taylor & Francis
Chikungunya virus (CHIKV) is a re-emerging alphavirus which causes severe and
prolonged arthralgic febrile illness. The recent global spread of the virus and lack of …

Peptide aptamer-based time-resolved fluoroimmunoassay for CHIKV diagnosis

T Liu, C Gao, J Wang, J Song, X Chen, H Chen, X Zhao… - Virology Journal, 2023 - Springer
Background Chikungunya virus (CHIKV) and Dengue virus (DENV) have similar clinical
symptoms, which often induce misdiagnoses. Therefore, an antigen detection diagnostic …

Construction of a chikungunya virus, replicon, and helper plasmids for transfection of mammalian cells

M Colunga-Saucedo, EI Rubio-Hernandez… - Viruses, 2022 - mdpi.com
The genome of Alphaviruses can be modified to produce self-replicating RNAs and virus-
like particles, which are useful virological tools. In this work, we generated three plasmids for …

Chikungunya and zika viruses: Co-circulation and the interplay between viral proteins and host factors

S Wichit, N Gumpangseth, R Hamel, S Yainoy, S Arikit… - Pathogens, 2021 - mdpi.com
Chikungunya and Zika viruses, both transmitted by mosquito vectors, have globally re-
emerged over for the last 60 years and resulted in crucial social and economic concerns …

Integrative, in silico and comparative analysis of breast cancer secretome highlights invasive-ductal-carcinoma-grade progression biomarkers

SL Kastora, G Kounidas, V Speirs, YA Masannat - Cancers, 2022 - mdpi.com
Simple Summary Globally, breast cancer (BC) is the most frequently diagnosed cancer in
women. Rapid advances in omics technologies have enabled the identification of …